Table 1.
Name | Promoter | Lab | Concentrationa | Minimum titreb | References |
---|---|---|---|---|---|
LV-C | CMV | Amsterdam | 99 μg/ml of P24 | 6 × 105 TU/μl (HEK cells) | Naldini et al. (1996a), Hendriks et al. (2007), |
LV-D | CMV | London | 1.44 × 109 gen/ml | 8 × 105 TU/μl (HEK cells) | Dull et al. (1998), Yáñez-Muñoz et al., 2006 |
LV-P | PGK | Lausanne | 479 μg/ml of P24 | ∼106 TU/μl (SCTM cells) | Déglon et al. (2000) |
gen: genomes, by Q-PCR.
TU: transducing units. These titres are approximate values derived from the number of cells positive by chondroitinase immuno-staining 3 days after transduction of a subconfluent monolayer, quoted for the cell type which gave the highest titre.