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Down-regulation of expression of vascular endothelial growth factor by TTF1 (× 200). Brown staining indicates vascular endothelial growth factor positive. Different doses of compound were used as treatments in the HepG-2-transplanted nude mice as follows: A: sTTF1 (5 μmol/kg); B: TTF1 (10 μmol/kg); C: lTTF1 (20 μmol/kg); D: Apigenin (40 μmol/kg); E: Con (control group treated with normal saline).
