Table 3.
Correlation between methylation and recurrence in esophageal squamous cell carcinoma patients
| Gene | n |
Recurrence |
Crude OR (95% CI) | Pvalue | Adjusted OR1 (95% CI) | P value1 | |
| No | Yes | ||||||
| SFRP-1 | |||||||
| Negative | 57 | 49 | 8 | 1.00 | < 0.001 | 1.00 | < 0.001 |
| Positive | 24 | 11 | 13 | 7.24 (2.42-21.68) | 10.8 (2.54-46) | ||
| WIF-1 | |||||||
| Negative | 52 | 42 | 10 | 1.00 | 0.069 | 1.00 | 0.107 |
| Positive | 29 | 18 | 11 | 2.57 (0.93-7.11) | 2.61 (0.8-8.47) | ||
| DKK-3 | |||||||
| Negative | 51 | 44 | 7 | 1.00 | 0.001 | 1.00 | 0.003 |
| Positive | 30 | 16 | 14 | 5.50 (1.88-16.08) | 6.07 (1.73-21.28) | ||
| RUNX-3 | |||||||
| Negative | 52 | 45 | 7 | 1.00 | < 0.001 | 1.00 | 0.001 |
| Positive | 29 | 15 | 14 | 6.00 (2.04-17.65) | 7.81 (2.30-47) | ||
1
Adjusted for age, gender, smoking, drinking, stage, surgical operation and chemo-/radio-therapy. CI: Confidence intervals; OR: Odds ratios.