Table 1.
Predictive Capability of Clinical Assessment or Qualitative CBR-Time Curve Patterns for Survival, Histological Grade, and Tissue Necrosis on POD 3
| Clinically | NIR Filling Defect | NIR Inflow Peak | AI Pattern | |
|---|---|---|---|---|
| Non-viable | Present | Absent | Present | |
| Animal Survival | ||||
| Sensitivity | 100% | 97% | 86% | 53% |
| Specificity | 47% | 73% | 90% | 95% |
| Accuracy | 55% | 77% | 90% | 88% |
| P value* | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 |
| Odds Ratio(CI 95%) | 81.86 (4.984–1345) | 124.4 (16.79–922.2) | 62.74 (24.00–164.0) | 24.31 (10.47–56.43) |
| Histological Grade | ||||
| Sensitivity | 94% | 87% | 60% | 35% |
| Specificity | 55% | 85% | 96% | 98% |
| Accuracy | 67% | 85% | 85% | 79% |
| P value* | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 |
| Odds Ratio (CI 95%) | 20.72 (8.059–53.27) | 40.42 (19.26–84.81) | 37.22 (16.30–84.97) | 37.05 (10.94–125.5) |
| Clinical Necrosis | ||||
| Sensitivity | 93% | 92% | 60% | 33% |
| Specificity | 58% | 93% | 100% | 100% |
| Accuracy | 70% | 92% | 85% | 76% |
| P value* | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 |
| Odds Ratio (CI 95%) | 19.16 (8.435–43.55) | 156.6 (89.50–747.7) | 564.8 (34.21–9323) | 194.3 (11.75–3214) |
*
Fisher exact test. AI Pattern = arterial insufficiency pattern; CI 95% = confidence interval of 95%.