Kaplan–Meier Curves for the Primary End Point, According to Intention-to-Treat Analysis.
Reinfarction events are those confirmed to meet the OAT definition (see methods).
Risk factors for the primary endpoint on multivariate analysis included age [HR 1.14 per 10 years older, p=0.006]; history of diabetes at study entry [HR 1.70, p<0.0001]; lower eGFR [HR 1.08 per 10 ml/min/1.73 m2 decrease, p=0.002); lower EF at baseline [HR 1.34 per 10 percentage points lower, p<0.001]; history of cerebrovascular disease [HR 1.81, p=0.001], history of PCI before study entry [HR 1.70, p=0.002];shorter time from qualifying MI to randomization [HR=1.03 p<0.0001]; history of peripheral vascular disease [HR 1.74, p=0.002] and HF at baseline [HR 1.41, p=0.0006], which was defined as one or more of the following: history of HF prior to randomization, rales on examination, S3 gallop on examination, Highest Killip class >1 during index MI prior to randomization, Highest NYHA class >I prior to index MI, or NYHA Class II at randomization.