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. Author manuscript; available in PMC: 2011 Dec 12.
Published in final edited form as: Mol Pharm. 2010 Apr 5;7(2):491–500. doi: 10.1021/mp900227a

Figure 5.

Figure 5

Accumulation in cells+bile (black bars) and cells (white bars) after a 10-min incubation with 1 μM [3H]taurocholate in mouse hepatocytes cultured in Biocoat™/Matrigel™ (BC/MG) or Biocoat™/gelled-collagen (BC/GC) sandwich configuration in six-well plates and maintained with DMEM for 3 or 4 days (Mean ± S.E.M., n=3). Cellular accumulation (white bars) of [3H]taurocholate was significantly increased on day 3 compared to day 4, and significantly greater when cultured in BC/MG configuration compared to the BC/GC configuration on both days 3 and 4 of culture. * p < 0.05