Table 2.
Plasma Hormone Concentrations in Study 2
| Hormone | Vehicle Treated | E2SO4 Treated | Statistics |
|---|---|---|---|
| ACTH (pg/mL) | 21 ± 1 | 27 ± 2 | F = 13.1; P = .001 |
| POMC (nmol/L) | 33 ± 7 | 42 ± 6 | F = 0.79; P = .38 |
| Cortisol (ng/mL) | 5.4 ± 3.7 | 20.3 ± 7.6 | F = 5.88; P = .02 |
| DHEAS (pg/mL) | 12 ± 5 | 17 ± 2 | F = .818; P = .38 |
| Progesterone (ng/mL) | 5.8 ± 0.5 | 4.8 ± 0.3 | F = 2.7; P = .11 |
| Estradiol (pg/mL) | 29 ± 3 | 229 ± 32 | F = 37.9; P < .001 |
| Estradiol-3-sulfate (pg/mL) | 413 ± 55 | 1139 ± 99 | F = 40.9; P < .001 |
| ACTH/POMC ratio | 1.2 ± 0.4 | 1.2 ± 0.4 | F = 0.03; P = .87 |
Abbreviations: ACTH, adrenocorticotropic hormone; POMC, proopiomelanocortin; DHEAS, dehydroepiandrosterone sulfate; E2SO4, estradiol-3-sulfate.