Table 1.

Demographic data and clinical features of the study subjects

	Controls (n=61)	Mild VaD (n = 30)	Moderate VaD (n = 40)	p value
Age, years	68.8 ±7.4	70.1 ±8.4	71.7 ±8.1	0.187
Education, years	9.3 ±3.3	9.7 ±3.2	7.5±2.5a	0.005
Females, %	67.4	46.2	64.4	0.066
MMSE	28.3±1.5b	22.2±1.4b	15.4±2.9b	<0.001
MoCA	25.2±3.8b	16.4±3.7b	10.0±5.1b	<0.001
CLOX1	12.4±1.49b	8.9±3.4b	5.8±4.1b	<0.001
CLOX2	13.8±1.2b	12.1±2.4b	8.6±3.9b	<0.001

Means (crude) ± SD.

^aModerate VaD < mild VaD and controls (p = 0.005).

^bModerate VaD < mild VaD < controls (p < 0.001).