Table 2.
Univariate analysis on potential prognostic factors for overall survival after primary diagnosis, ns - not significant, CI - confidence interval, meth - methylated.
| Factor | p-value (unadjusted, log-rank) | Hazard ratio | 95%-CI |
|---|---|---|---|
| MGMT methylation status (not meth/meth) | 0.009 | 3.6 | 1.3 - 9.7 |
| Sex (male/female) | ns (0.4) | 1.2 | 0.8 - 1.8 |
| Re-RT (no/yes) | ns (0.5) | 1.7 | 0.4 - 7.0 |
| Concomitant TMZ (no/yes) | 0.04 | 2.6 | 1.0 - 6.8 |
| Adjuvant TMZ (no/yes) | 0.001 | 4.1 | 1.7 - 9.8 |
| Age category (< 60 y, ≥ 60 y) | ns (0.1) | 0.5 | 0.2 - 1.2 |
| Type of resection (complete/incomplete) | ns (0.83) | 0.9 | 0.4 - 2.0 |
| RPA class (V/IV/III) | ns (0.08) | IV (0.5), III (0.2) | IV (0.2 - 1.2), III (0.02 - 1.4) |