Adequate method of randomization |
57 |
43.5% |
Adequate method of allocation concealment |
41 |
31.3% |
Similarity at baseline regarding the most important prognostic indicators |
89 |
67.9% |
Appropriate patient blinding to the intervention |
30 |
22.9% |
Appropriate care provider blinding to the intervention |
4 |
3.1% |
Appropriate outcome assessor blinding to the intervention |
66 |
50.4% |
Similar or no cointerventions between-groups |
40 |
30.5% |
Acceptable compliance in all groups |
53 |
40.5% |
Described and acceptable drop-out rates |
99 |
75.6% |
Similarity of timing of the outcome assessment in all groups |
118 |
90.1% |
Inclusion of an intention-to-treat analysis |
57 |
45.5% |
Absence of selective outcome reporting |
78 |
59.5% |
Absence of other potential bias |
7 |
5.3% |
|
Total risk of bias scores (max 13); median (IQR) |
6 |
4–7 |