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. Author manuscript; available in PMC: 2012 Oct 28.
Published in final edited form as: Circ Res. 2011 Sep 15;109(10):1162–1172. doi: 10.1161/CIRCRESAHA.111.253807

Figure 5. Evidence to suggest mild pathological remodelling in LCR over HCR rats.

Figure 5

(A) Transverse (T) tubule density relative to cardiomyocyte cell size decreased in old LCR but not old HCR rats. (B) Representative examples of cardiomyocytes stained with Di-8-ANEPPS for imaging of T-tubules in old LCR and HCR rats. (C) Higher systolic and (D) diastolic blood pressures in the LCR vs. HCR might be responsible for part of the cardiac cellular changes. *: p<0.05 age-matched LCR vs. HCR. (E) Light micrographs (hematoxylin and eosin stained) of myocardium from representative HCR (left) and LCR (right, both old age). Vacuolization marked with arrows and interstitial fibroplasia marked by letter F. Bar = 50 μm.