Figure 3.

Widespread expression of K^b-LTFNYRNL, but not LTFNYRNL without K^b, blunts the accumulation of Tet^H60+ cells. K^b−/−, actH60→actH60, actH60.K^b−/−→actH60.K^b−/−, actH60→actH60.K^b−/−, and actH60.K^b−/−→actH60 mice were irradiated and reconstituted with 6 × 10⁶ BM cells, 2.4 × 10⁶ CD8 cells, and 10⁵ CD4 cells from C3H.SW mice. (A) Representative flow cytometry from day 14 (gated on Ly9.1⁺CD8⁺ cells). (B) Total numbers of Ly9.1⁺CD8⁺ Tet^H60+ cells per spleen at day 14. P = .0571, comparing actH60→actH60 to actH60→actH60.Kb^−/− mice.