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. 2011 Dec 12;6(12):e28582. doi: 10.1371/journal.pone.0028582

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Liao et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Ophthalmic examination of the proband from one of the families showed grey lines in the corneal epithelium, one of the characteristics of MECD. Slit lamp photography revealed multiple microcysts in the anterior epithelium (B) and uneven corneal topography secondary to damage and scarring of the underlying basement membrane (C).