Table 1. Basic characteristics of patients infected with HCV.
IL28B rs8099917 | Total | Major | Minor | P-value |
No. of patients | 202 | 134 | 68 | |
Age, y | 55.4±11.7 | 56.6±11.1 | 53.1±12.4 | 0.0431 |
Gender (M/F) | 101/101 | 64/70 | 37/31 | NS |
HCV RNA (H/L/U) | 191/10/1 | 125/9/0 | 66/1/1 | NS |
Genotype (G1/G2/U) | 166/34/2 | 111/22/1 | 55/12/1 | NS |
ASL (IU/L) | 57.2±43.9 | 56.4±47.9 | 58.7±34.9 | NS |
ALT (IU/L) | 69.9±60.0 | 67.5±63.3 | 74.7±53.2 | NS |
G-GTP (IU/L) | 52.5±60.6 | 42.5±38.3 | 72.0±86.6 | 0.000949 |
WBC (/mm3) | 5,240±1,520 | 5,270±1,620 | 5,170±1,320 | NS |
Hb (g/dL) | 14.0±1.3 | 14.0±1.2 | 14.1±1.3 | NS |
Platelets (×104/mm3) | 17.3±5.8 | 17.5±5.7 | 17.1±6.0 | NS |
DM (+/−/U) | 30/169/3 | 18/114/2 | 12/55/1 | NS |
US (CH/LC/U) | 163/33/6 | 112/19/3 | 51/14/3 | NS |
We defined IL28B rs8099917 TT (n = 134) as major type and TG (n = 64) and GG (n = 4) as minor type.
H, high viral load (±5 log IU/mL); L, low viral load (<5 log IU/mL); G1, genotype 1; G2, genotype 2; U, unknown; WBC, white blood cell count; Hb, hemoglobin; DM, diabetes mellitus; US, ultrasound finding; CH, chronic hepatitis; LC, liver cirrhosis; NS, not significant.