Table 2. No correlation between STAT1-nuclear translocation and IL28B genotypes.
| IL28B rs8099917 | Total | Major | Minor | P-value |
| No. of patients | 79 | 53 | 26 | |
| Age, y | 54.4±11.6 | 55.8±10.4 | 51.5±13.5 | NS |
| Gender (M/F) | 37/42 | 24/29 | 13/13 | NS |
| ASL (IU/L) | 58.0±51.5 | 60.0±59.6 | 54.0±29.2 | NS |
| ALT (IU/L) | 69.2±61.7 | 71.1±70.4 | 65.4±39.5 | NS |
| G-GTP (IU/L) | 40.8±25.4 | 35.6±24.0 | 51.4±25.3 | 0.00849 |
| WBC (/mm3) | 5,190±1,320 | 5,330±1,420 | 4,900±1,070 | NS |
| Hb (g/dL) | 14.4±1.2 | 14.3±1.2 | 14.5±1.2 | NS |
| Platelets (×104/mm3) | 17.0±6.5 | 17.3±6.1 | 16.5±7.3 | NS |
| DM (+/−/U) | 12/67/0 | 6/47/0 | 6/20/0 | NS |
| US (CH/LC/U) | 63/15/1 | 42/11/0 | 21/4/1 | NS |
| VR/Null Responder | 51/28 | 39/14 | 12/14 | 0.0319 |
| RVR (+/−) | 2/77 | 1/52 | 1/25 | NS |
| EVR (+/−) | 28/51 | 24/29 | 4/22 | 0.0182 |
| SVR (+/−) | 29/50 | 24/29 | 5/21 | 0.0445 |
| Liver Biopsy | ||||
| F (F1/F2/F3/F4) | 29/25/15/10 | 20/16/10/7 | 9/9/5/3 | NS |
| A (A1/A2/A3) | 28/43/8 | 20/29/4 | 8/14/4 | NS |
| Nuclear-STAT1 (%) | ||||
| Zone 1 | 9.14±8.11 | 8.65±7.67 | 10.1±9.03 | NS |
| Zone 2 | 3.78±3.94 | 3.74±4.20 | 3.86±3.43 | NS |
| Zone 3 | 7.41±7.07 | 6.90±6.76 | 8.44±7.71 | NS |
| Total | 6.57±5.29 | 6.28±5.58 | 7.16±4.69 | NS |
We defined IL28B rs8099917 TT (n = 134) as major type and TG (n = 64) and GG (n = 4) as minor type.
U, unknown; WBC, white blood cell count; Hb, hemoglobin; DM, diabetes mellitus; US, ultrasound findings; CH, chronic hepatitis; LC, liver cirrhosis; VR, virological responder; RVR, rapid virological responder; EVR, early virological responder; SVR, sustained virological responder; F, Staging of Fibrosis; A, Grading of Activity; nuclear-STAT1, STAT1-nuclear translocation; NS, not significant.