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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Diabetes Obes Metab. 2011 Nov 22;14(1):58–66. doi: 10.1111/j.1463-1326.2011.01488.x

Figure 7. Sex differences in insulin resistance.

Figure 7

On the 10th week, ITT was performed after a 6hr fast. Mice were injected with 0.75U/g of bodyweight of insulin, and a small drop of blood was collected from the tail to measure blood glucose levels at 0, 15, 30, 60, 120 minutes after injection. Panel A: After 10 weeks of consuming a high-fat diet, male and ovx-female mice experience significantly more insulin resistance compared to novx-female and ovx-female+E mice. Area under the curve was calculated and is graphically shown in Panel B. ** Significantly different compared to novx-female and ovx-female+E consuming the high fat diet, p<0.001 (n=10).