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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Immunobiology. 2011 May 30;217(5):548–557. doi: 10.1016/j.imbio.2011.05.014

Figure 2.

Figure 2

Effect of niacin therapy on the migration of DCs from skin to draining lymph nodes. Mice were fed control chow (Ctl) or 1% niacin-supplemented chow (Niacin) for two weeks. 18 hours after FITC-containing contact sensitizer solution was applied to the shaved flanks of anesthetized mice, animals were sacrificed, brachial and axillary lymph nodes were removed and pooled by side, and FITC+ migrated DCs quantified by flow cytometry in (A) wild-type or (B) apoE−/− mice. (C) Total lymph node cellularity was quantified by manual counting. Each dot represents a pool of brachial and axillary lymph node from one side of a mouse (two dots per mouse). Each experimental condition was repeated 3-6 times with 3-5 mice per condition. P-values, depicted within each graph, were determined with an unpaired T-test.