Skip to main content
. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Immunobiology. 2011 May 30;217(5):548–557. doi: 10.1016/j.imbio.2011.05.014

Figure 3.

Figure 3

Effect of niacin therapy on the migration of DCs from lung to draining lymph nodes. ApoE−/− or wild-type mice were fed control chow (Ctl) or 1% niacin-supplemented chow (Niacin) for two weeks. (A) Total lymph node cellularity was quantified by manual counting of the inguinal lymph node in ApoE−/− mice and the medial iliac lymph node in wild-type mice. (B) 24 hours after a solution of FITC-ovalbumin and LPS was delivered intranasally to anesthetized mice, animals were sacrificed, mediastinal lymph nodes were removed, and FITC+ migrated DCs quantified by flow cytometry in wild-type. Each dot represents a mouse. Each experimental condition was repeated 2 times with 3-5 mice per condition. P-values, depicted within each graph, were determined with an unpaired T-test.