Table 6.
Genotype distribution of four SNPs in FGFR2a
| rs2981582 | rs2981578 | rs10736303 | rs7895676 | Number of patients |
|---|---|---|---|---|
| CT | AG | AG | CT | 29 |
| TT | GG | GG | CC | 22 |
| CC | AA | AA | TT | 21 |
| CT | GG | GG | CC | 7 |
| CC | AG | AG | CT | 5 |
| TT | AA | AA | TT | 1 |
| Total | 85b |
aFGFR2: fibroblast growth factor receptor 2 gene. The number of patients who carry each combination of the four genotypes is shown in the right-hand column. Although we have no haplotype information, the genotype distribution shows the strong linkage disequilibrium present within this region. The alleles associated with increased breast cancer risk are rs2981582: T; rs2981578: G; rs10736303: G; and rs7895676: C. bFor the remaining13 patients, only rs2981578 was genotyped; of these patients, 5 carried AA, 5 carried AG and 3 carried GG.