Table 1.
Mammary gland transplantation data and logistic regression analysis
| MG transplantation dataa | Logistic regression analysisb | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| S:S | S:R | R:S | R:R | Total | Independent | Coefficient | P value | ||
| Transplant MG present | 31 | 72 | 22 | 88 | 213 | MG transplantation efficiency | Donor effect | -0.3502 | 0.6449 |
| Transplant MG absent | 6 | 11 | 3 | 11 | 31 | Recipient effect | -0.4372 | 0.4423 | |
| Percentage of MG present | 84% | 87% | 88% | 89% | 87% | Donor × recipient | 0.3389 | 0.7056 | |
| 0 carcinomas | 15 | 50 | 12 | 66 | 143 | ||||
| 1 carcinoma | 13 | 17 | 10 | 19 | 59 | MG transplant carcinoma susceptibility |
Donor effect | -0.2468 | 0.6588 |
| 2 carcinomas | 3 | 4 | 0 | 3 | 10 | Recipient effect | -0.8855 | 0.0447c | |
| 3 carcinomas | 0 | 1 | 0 | 0 | 1 | Donor × recipient | 0.0307 | 0.9629 | |
| Percentage of MGs with 1 carcinoma | 52% | 31% | 45% | 25% | 33% | ||||
aTransplant groups (donor/recipient): S:S, susceptible/susceptible; S:R, susceptible/resistant; R:S, resistant/susceptible; R:R, resistant/resistant. bLogistic regression was used to estimate the effect of donor and recipient and the interaction between donor and recipient for the dependent variables mammary gland (MG) transplantation efficiency (outcome = histologically determined presence or absence of MG development at transplant site) and MG transplant carcinoma susceptibility (outcome = tumor presence or absence at transplant site) in susceptible congenic control and Mcs5a-resistant congenic reciprocal (donor, recipient) transplant groups. cStatistically significant.