Table 1.
Patient Information. Table 1 depicts demographic data, pretreatment characteristics, and treatment characteristics for the axial EWS and appendicular EWS groups.
| Axial EWS (n = 34, 51%) | Appendicular EWS (n = 33, 49%) | Total (n = 67) | P value | |
|---|---|---|---|---|
| Pretreatment Factors | ||||
| Median Age | 25.1 | 28.7 | 26.9 | 0.23 |
| No. male | 21 (62%) | 20 (61%) | 41 (61%) | 0.30 |
| No. female | 13 (38%) | 13 (39%) | 26 (39%) | — |
| No. bone | 31 (91%) | 26 (79%) | 57 (85%) | 0.19 |
| No. soft tissue (ST) | 3 (9%) | 7 (21%) | 10 (15%) | — |
| No. with metastases at diagnosis | 10 (29%) | 5 (15%) | 15 (22%) | 0.33 |
| No. bone lesions over 8 cm | 21 (62%) | 17 (52%) | 38 (57%) | 0.9 |
| No. bone lesions under 8 cm | 10 (29%) | 9 (27%) | 19 (28%) | — |
| No. ST lesions over 5 cm | 1 (3%) | 4 (12%) | 5 (7%) | 1.0 |
| No. ST lesions under 5 cm | 2 (6%) | 3 (9%) | 5 (7%) | — |
|
| ||||
| Treatment Factors | ||||
| No. receiving definitive treatment | 25 (74%) | 29 (88%) | 54 (81%) | 0.22 |
| No. receiving definitive surgery | 16 (47%) | 28 (85%) | 44 (66%) | 0.0018 |
| No. receiving definitive XRT | 9 (26%) | 1 (3%) | 10 (15%) | 0.013 |
| No. not receiving surgery or XRT | 9 (26%) | 4 (12%) | 13 (19%) | 0.22 |
| No. receiving adjuvant XRT | 8 (24%) | 2 (6%) | 10 (15%) | 0.045 |
|
| ||||
| Outcome Parameters | ||||
| No. positive margins | 6 (18%) | 3 (9%) | 9 (13%) | 0.0031 |
| No. local recurrences | 5 (15%) | 0 (0%) | 5 (7%) | 0.053 |
| No. ANED | 10 (29%) | 22 (67%) | 32 (48%) | |
| No. AWED | 2 (6%) | 1 (3%) | 3 (4%) | |
| No. DOD | 22 (65%) | 10 (30%) | 32 (48%) | |
| % 5-year OS | 29% | 66% | 0.002 | |