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Effects of aspirin on the platelet activity in COX 2 −/− knockout mice.
| ASA | Placebo | 100 mg/kg | 1 mg/kg | Dil 5 | Dil 9 | Dil 15 |
|---|---|---|---|---|---|---|
| IHT (sec) | 327.3 ± 103.8 | 212.2 ± 109.3 | 288.1 ± 98.7 | 300.9 ± 131.4 | 336.5 ± 77.7 | 245.5 ± 123.9 |
| NE | 9.0 ± 3.9 | 3.29 ± 2.36* | 7.0 ± 4.5 | 6.50 ± 3.2 | 5.25 ± 3.24 | 8.11 ± 2.76 |
| DE (min) | 4.5 ± 1.73 | 1.29 ± 1.11* | 3.0 ± 2.4 | 2.38 ± 1.51 | 2.25 ± 1.58 | 3.55 ± 1.01 |
*P < 0.05 indicates a statistically significant difference with the placebo group.
