Table 1.
Intrinsic electrophysiological properties of striatal NPY interneurons
| Parameter | Input resistance (MΩ) | RMP (mV) | AP threshold (mV) | AP width 50% (ms) | AP amplitude (mV) | AHP amplitude (mV) | AHP duration (ms) | Spontaneous firing rate (Hz) | LTS | Ih ratio |
|---|---|---|---|---|---|---|---|---|---|---|
| NPY–PLTS (44) | 744 ± 51 (310–1702) | −63 ± 1 (−79 to −51) | −45 ± 1 (−53 to −38) | 1.3 ± 0.05 (0.75–2) | 74 ± 1.8 (56–108) | 17 ± 1 (9–25) | 134 ± 11 | 6.4 + 0.5 (2–12) 30/44 | 35/44 | 1.1 ± 0.005 (1.01–1.4) 43/44 |
| NPY–NGF (19) | 142 ± 13* (74–260) | −88 ± 1* (−95 to −79) | −44 ± 1 (−48 to −39) | 1.25 ± 0.08 (0.74–1.9) | 80 ± 2 (64–101) | 26 ± 1* (20–32) | 140 ± 5 | 0/19 | 0/19 | 1 ± 0 |
All values are means ± SEM. The numbers in parentheses refer to the range of values. n refers to number of neurons from which the measurements were obtained. AP, Action potential; RMP, resting membrane potential; AHP, afterhyperpolarizing; LTS, low threshold spike.
*p < 0.001; #p < 0.05, Student's two-tailed t test.