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Skin symptoms and time to onset of the NSAID-induced hypersensitivity.
| Group of patients | Time to onset* | NSAID-induced skin symptoms | ||||
|---|---|---|---|---|---|---|
| Median | <6 H | AO | AO + Urticaria | Urticaria | ||
| Grade I | n = 38 | 8 H | 14 (37%) | 18 (47%) | 9 (24%) | 11 (29%) |
| Grade II | n = 22 | 1 H | 21 (95%) | 12 (55%) | 7 (32%) | 3 (14%) |
|
| ||||||
| Total | n = 60 | 4.5 H | 35 (58%) | 30 (50%) | 16 (27%) | 14 (23%) |
*The time to onset of symptoms after NSAID intake was shorter in patients with grade II hypersensitivity than in patients with grade I (P < 0.0001).
