Table 2.
Analysis of genetic factors by case–control status (cases vs. controls)
| All subjects | Men | Women | ||||||
|---|---|---|---|---|---|---|---|---|
| Genetic polymorphism | Reference group | Studied groups | OR | P Value | OR | P Value | OR | P Value |
| GSTM1 | Null | Positive | 0.99 (0.61–1.61) | 1 | 0.82 (0.45–1.50) | 0.54 | 1.53 (0.66–3.57) | 0.40 |
| GSTT1 | Null | Positive | 1.86 (0.82–4.24) | 0.16 | 2.23 (0.64–7.74) | 0.31 | 1.23 (0.40–3.80) | 1 |
| EPHX*3 | YY | YH | 1.09 (0.65–1.84) | 0.79 | 0.81 (0.42–1.57) | 0.62 | 1.99 (0.80–4.50) | 0.16 |
| YY | HH | 0.96 (0.45–2.05) | 1 | 0.52 (0.20–1.35) | 0.20 | 2.69 (0.75–9.67) | 0.12 | |
| YY | YH/HH | 1.06 (0.65–1.71) | 0.90 | 0.71 (0.39–1.30) | 0.29 | 2.13 (0.90–5.05) | 0.09 | |
Odds ratios with 95% confidence intervals for polymorphisms of GSTM1, GSTT1, and EPHX3 were analyzed in 79 cases of cryptogenic polyneuropathy (54 men, 25 women) and 398 controls from the general population (198 men, 200 women). The chi-square test was used and the analysis was completed with Fischer's exact test in groups with less than five respondents. Comparisons were considered significant if P-values were <0.05.