Table 3.

Effects of genetic polymorphisms in different exposures (exposed cases and controls)

Genetic polymorphisms	Studied groups	Exposure	Odds ratio	P Value
GSTM1	Null versus positive	Smoking	1.08 (0.56–2.10)	0.87
GSTT1	Null versus positive	Smoking	3.72 (0.85–16.2)	0.08
EPHX*3	YH versus YY	Smoking	1.40 (0.69–2.82)	0.38
	HH versus YY	Smoking	0.57 (0.18–1.82)	0.44
	YH/HH versus YY	Smoking	1.14 (0.58–2.22)	0.74
GSTM1	Null versus positive	Solvent	0.46 (0.18–1.14)	0.12
GSTT1	Null versus positive	Solvent	1.31 (0.28–6.1)	1
EPHX*3	YH versus YY	Solvent	0.72 (0.27–1.91)	0.63
	HH versus YY	Solvent	0.30 (0.06–1.40)	0.14
	YH/HH versus YY	Solvent	0.55 (0.22–1.34)	0.27
GSTM1	Null versus positive	Pesticides	0.98 (0.19–4.94)	1
GSTT1	Null versus positive	Pesticides	0.25 (0.01–4.51)	0.39
EPHX*3	YH versus YY	Pesticides	1.33 (0.24–7.28)	1
	HH versus YY	Pesticides	0.80 (0.07–9.67)	1
	YH/HH versus YY	Pesticides	1.18 (0.23–5.89)	1
GSTM1	Null versus positive	Generalized anesthesia	1.09 (0.62–1.90)	0.78
GSTT1	Null versus positive	Generalized anesthesia	1.05 (0.94–1.17)	0.55
EPHX*3	YH versus YY	Generalized anesthesia	1.10 (0.60–2.11)	0.76
	HH versus YY	Generalized anesthesia	0.95 (0.39–2.32)	1
	YH/HH versus YY	Generalized anesthesia	1.06 (0.61–1.85)	0.89
GSTM1	Null versus positive	Private water	0.78 (0.43–1.43)	0.45
GSTT1	Null versus positive	Private water	1.66 (0.57–4.91)	0.48
EPHX*3	YH versus YY	Private water	1.11 (0.58–2.14)	1
	HH versus YY	Private water	1.01 (0.41–2.50)	1
	YH/HH versus YY	Private water	1.09 (0.60–1.97)	0.88

Odds ratios with 95% confidence intervals for polymorphisms of GSTM1, GSTT1, and EPHX3 are given for exposed cases of cryptogenic polyneuropathy and exposed controls from the general population. The chi-square test was used and the analysis was completed with Fischer's exact test in groups with less than five respondents. Comparisons were considered significant if P-values were <0.05.