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Effects of Kcne2 deletion on CPe and CSF parameters
| Genotype | CPe Em (mV) | CSF pH | CSF [K+] (mM) | Serum [Cl−] (mM) | CSF [Cl−] (mM) |
|---|---|---|---|---|---|
| Kcne2+/+ | −39.5 ± 1.5 (10) | 7.5 ± 0.3 (10) | 3.2 (9) | 107 ± 1 (6) | 118 ± 5 (5) |
| Kcne2−/− | −48.1 ± 1.9 (12)* | 7.3 ± 0.4 (10) | 3.1 (10) | 111 ± 1 (6) | 134 ± 6 (5)* |
CPe and CSF parameters are indicated as means ± se, where available, with n values in parentheses; absence of se indicates that intragenotype samples were pooled before measurement.
P < 0.05 vs. Kcne2+/+.
