Figure 3. In vivo infectivity of Tulahuen dhfr-ts^+/− and Tulahuen wild type metacyclic trypomatigotes.

(A) Parasitemia curves of IFNγ^−/− mice inoculated with 5×10⁴ metacyclic trypomastigotes of Tulahuen wild type and dhfr-ts^+/− parasites. (B) Parasite load of nude mice inoculated with 5×10⁴ metacyclic trypomastigotes of Tulahuen wild type and dhfr-ts^+/− parasites at day 20 post-infection. (C) Parasitemia curves of Balb/c mice inoculated with 2×10⁴ metacyclic trypomastigotes of Tulahuen wild type and 2×10⁵ metacyclic trypomastigotes of Tulahuen dhfr-ts^+/− metacyclic trypomastigotes. Values are given as means; error bars indicate standard errors of the means.