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. 2011 Dec 13;5(12):e1422. doi: 10.1371/journal.pntd.0001422

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Total hamster immunoglobulin responses to immunogens were measured by ELISA. Geometric mean end-point titers and standard deviations (n = 4) are shown after the first (gray), second (blue), and third (black) immunizations. In all cases, pre-immune sera were negative. Recombinant LigA proteins are represented by their domain numbers. Asterisks indicate proteins that provided 100% protection against lethal challenge.