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. 2011 Dec 13;5(12):e1427. doi: 10.1371/journal.pntd.0001427

Figure 3. The detection of reduced efficacy when defined as ‘true’ drug efficacy <90% and <95%.

Figure 3

Only combinations of sample size (n), mean fecal egg count before drug administration (mean pre-DA FEC), detection limit and aggregation (k), which resulted in a reliable FECRT (sensitivity (Se) and specificity (Sp) ≥85%) are shown. Also shown are TDE limits for Se and Sp, which caused Se and Sp <85%.