Table 1. A detailed example to illustrate the data generated by Monte Carlo simulation.
Host ID | Pre-drug administration FEC (EPG) | Post-drug administration FEC (EPG) | ||
True counts | Observed counts | True counts | Observed counts | |
A | 796 | 840 | 398 | 288 |
B | 120 | 168 | 60 | 0 |
C | 172 | 144 | 86 | 96 |
D | 212 | 288 | 106 | 120 |
E | 258 | 240 | 129 | 168 |
F | 100 | 0 | 50 | 24 |
Mean | 276.2 | 280 | 138.1 | 116 |
FECRT (%) | 50.0 | 58.6 |
The table shows a random sample of six subjects (A–F) drawn from a parasite-host population with a mean pre-drug administration fecal egg count (FEC) of 250 eggs per gram of stool (EPG) and a k-value of 1, for a sample size of six in which a drug with a ‘true’ drug efficacy of 50% was evaluated by the fecal egg count reduction test using a detection technique with a detection limit of 24 EPG.