Table 2. The five trials used to validate the outcome of the classification trees.
Country (number of subjects, prevalence of STH) | Mean pre-DA FEC (EPG) | k | FECRT | Threshold of 90% | Threshold of 95% | ||
Required | Predicted | Required | Predicted | ||||
Brazil (n = 350, 30.6%) | |||||||
A. lumbricoides | 1,353 | 0.063 | 100 | 17 | 50–200 | 17 | 50–200 |
Hookworm | 101 | 0.097 | 97.5 | 30 | 10–49 | 176 | 50–200 |
Cambodia (n = 1,026, 31.9%) | |||||||
Hookworm | 183 | 0.121 | 97.6 | 20 | 10–49 | 75 | 50–200 |
Cameroon (n = 1,485, 44.1% ) | |||||||
A. lumbricoides | 2,906 | 0.061 | 99.2 | 12 | 50–200 | 15 | 50–200 |
T. trichiura | 331 | 0.042 | 39.2 | 32 | 50–200 | 22 | 50–200 |
Hookworm | 59 | 0.015 | 93.0 | 4405 | >200 | >5000 | 50–200 |
Ethiopia (n = 410, 61.0%) | |||||||
A. lumbricoides | 1,293 | 0.083 | 100 | 7 | 10–49 | 7 | 50–200 |
T. trichiura | 110 | 0.065 | 92.4 | 1152 | >200 | 1099 | 50–200 |
Hookworm | 74 | 0.144 | 99.7 | 12 | 10–49 | 14 | 50–200 |
Tanzania (n = 509, 95.3%) | |||||||
A. lumbricoides | 2,697 | 0.264 | 100 | 3 | 10–49 | 4 | 50–200 |
T. trichiura | 832 | 0.781 | 52.0 | 6 | 10–49 | 4 | 50–200 |
Hookworm | 706 | 0.572 | 95.3 | 78 | 10–49 | >5000 | >200 |
Cases highlighted in bold indicate an agreement between the required and the predicted sample size (the required sample size fell within the sample size interval predicted). Cases highlighted in italic indicate an underestimation of the required sample size (required sample size > upper limit of the predicted sample size interval). In the remaining cases, the required sample size was overestimated (required sample size > lower limit of the predicted sample size).