Figure 4. Anti-correlation of ALFF values across subjects between the systems in ALFF-FCN dichotomy.

Inter-ROI set analysis of ALFF-FCNs revealed a network dichotomy, which consisting of a high-level cognitive network system covering the DMN and TPN regions, and a low-level cognitive network system covering sensory regions The ALFF values within the high-level cognitive system (warm color) negatively correlated with those of the low-level cognitive (perceptive) system (cold color) (r = −0.822, P = 3.697×10⁻¹⁷).