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. Author manuscript; available in PMC: 2012 Dec 8.
Published in final edited form as: J Med Chem. 2011 Nov 9;54(23):8207–8213. doi: 10.1021/jm2012003

Table 1.

Growth inhibitory activities of artemisinin, arterolane, and compounds 5–8 against intraerythrocytic ring stage P. falciparum parasites.

Compound IC50 ± SEM (nM) P. falciparum strain
artemisinin 8.0 ± 0.1 FCB
arterolane 2.5 ± 0.3 a K1
5 17.9 ± 0.9 FCB
6 14.6 ± 1.1 FCB
7 24990 ± 1363 FCB
8 12.6 ± 0.4 FCB
a

IC50 value from reference 4.