Table 3.
Sensitivity, specificity, likelihood ratios, and predictive values of three titrated oxygen requirements for the prediction of one-year outcomes
| Pre-test probability 10% | Pre-test probability 50% | Pre-test probability 90% | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Sensitivity | Specificity | LR+ | LR− | PPV | NPV | PPV | NPV | PPV | NPV | |
| Derivation cohort | ||||||||||
| ≥1 L/min | 89% | 62% | 2.34 | 0.18 | 21% | 98% | 70% | 85% | 95% | 39% |
| ≥6 L/min | 44% | 89% | 4.00 | 0.63 | 31% | 93% | 80% | 61% | 97% | 15% |
| 15 L/min | 22% | 94% | 3.67 | 0.83 | 29% | 92% | 79% | 55% | 97% | 12% |
| Validation cohort | ||||||||||
| ≥1 L/min | 81% | 45% | 1.46 | 0.43 | 14% | 95% | 59% | 70% | 93% | 20% |
| ≥6 L/min | 55% | 86% | 3.96 | 0.52 | 31% | 95% | 80% | 66% | 97% | 18% |
| ≥15 L/min | 3% | 99.2% | 3.89 | 0.98 | 30% | 90% | 80% | 51% | 97% | 10% |
Abbreviation: LR+ = positive likelihood ratio, LR− = negative likelihood ratio, PPV = positive predictive value, NPV = negative predictive value.