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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Int J Cancer. 2011 Aug 12;130(11):2539–2548. doi: 10.1002/ijc.26257

Fig. 3.

Fig. 3

VASP Ser239 phosphorylation by GCC disrupts colon cancer cell filopodia. T84 cells were treated (with the PBS control or 1 μM ST to induce GCC signaling), imaged and analyzed for quantification of filopodia as in Fig. 2b. Cancer cells stably expressed the indicated MSCV-driven genes (see Material and Methods for details), including the controls GFP and VASP, and VASP-S157A (S157A), VASP-S239A (S239A) and VASP-AA (AA). Arrows in upper panels indicate representative filopodia. Bars, 10 μm. *, P < 0.05 versus respective control.