Table 3.
Top 25 ranked TFs for five microarray derived gene sets using tf-normal LSI model.
| tf-normal LSI model | |||||
|---|---|---|---|---|---|
| Rank | Interferon | IL-4 | Tunicamycin | GH | TGF-β1 |
| 1 | Irf7 | Stat4 | Yy1 | Nfkb1 | Smad7 |
| 2 | Irf1 | Stat6 | Atf4 | Nfkb2 | Smad9 |
| 3 | Irf8 | Irf1 | Zbtb7a | Rela | Postn |
| 4 | Irf5 | Irf5 | Atf7 | Rel | Smad6 |
| 5 | Irf2 | Stat1 | Nfyb | Ifi47 | Smad1 |
| 6 | Irf3 | Ifi47 | Zfp143 | Stat4 | Smad5 |
| 7 | Irf9 | Nfkb1 | Nfya | Irf7 | Hif1a |
| 8 | Stat1 | Itgal | Zbtb6 | Stat6 | Nfkb1 |
| 9 | Ifi47 | Stat2 | Atf2 | Irf1 | Stat3 |
| 10 | Stat2 | Irf3 | Elk1 | Stat1 | Egr1 |
| 11 | Stat4 | Irf7 | Nfyc | Stat2 | Nfatc1 |
| 12 | Nfkb1 | Pparg | Cebpe | Stat3 | Smad4 |
| 13 | Irf4 | Irf9 | Atf5 | Stat5a | Smad3 |
| 14 | Zfp143 | Foxp3 | Junb | Cebpb | Smad2 |
| 15 | Nfkb2 | Irf8 | Atf6 | Irf3 | Runx2 |
| 16 | Cebpe | Nfe2l2 | Bach1 | Stat5b | Stat5a |
| 17 | Zbtb6 | Stat3 | E4f1 | Irf9 | Gata4 |
| 18 | Elf4 | Foxo1 | Elk4 | Foxp3 | Tgif1 |
| 19 | Ddit3 | Irf2 | Atf3 | Foxo3 | Foxm1 |
| 20 | Stat3 | Ppard | Zfp148 | Irf5 | Gata6 |
| 21 | Rela | Ppara | Ddit3 | Itgal | Gata5 |
| 22 | Rel | Foxo3 | Jund | Irf8 | Nkx2-5 |
| 23 | Atf4 | Srebf1 | Hsf2 | Cebpe | Lef1 |
| 24 | Xbp1 | Srebf2 | Elk3 | Pparg | Cebpd |
| 25 | Hsf1 | Ddit3 | Hsf1 | E2f1 | Nkx3-2 |
TFs displayed in bold font were used as ground truth because they were targeted in the published study as critical regulators for each gene set.