Table 6.
Dataset | TF knockout | tf-normal | log-entropy | co-occurrence | CORE_TF |
---|---|---|---|---|---|
Interferon | Rel | 22 | 3 | 90 | [1--86]* |
IL-4 | Stat6 | 2 | 16 | 17 | 69 |
Tunicamycin | Ddit3 | 21 | 128 | 1 | -† |
GH | Stat5a/b | 13 | 50 | 29 | 9 |
TGF-β1 | Nfic | 241 | 233 | [205--433]§ | 289 |
*Using CORE_TF, Rel could be ranked anywhere between 1 and 86 as its associated motif V$CREL_01 had a p-value = 0 (rank 1) along with 85 other motifs. †The motif for Ddit3, V$CHOP_01 was not ranked by CORE_TF. §Using the abstract co-occurrence model, the TF Nfic could be ranked anywhere between 205 and 433 as it did not share any abstracts with any gene in the TGF-β1 dataset and therefore had a p-value of 1 along with 228 other TFs.