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. 2011 Oct 18;12(Suppl 10):S9. doi: 10.1186/1471-2105-12-S10-S9

Table 11.

Performance of the proposed algorithm when p53 is deactivated and Mdm2 is amplified.

p1 # networks # network-path pairs # paths result # SSD calculations
p1 = 0.1 730 1333 4 F 38,684
p1 = 0.3 2458 3810 4 F 69,050
p1 = 0.5 3937 7208 4 S 93,650
p1 = 0.7 4096 9009 4 S 113,612

Performance of the proposed algorithm when p53 is deactivated and Mdm2 is amplified. Several different values of β1 was used (by varying p1), and β2 was set to 0.1. The perturbation probability was assumed to be known (p = pcancer = 0.001).