Table 1.

Binding to commercial abrin and abrax.

Binder	Commercial Abrin			Abrax
	on, 1/Ms	off, 1/s	Kd, M a	on, 1/Ms	off, 1/s	Kd, M a
mAb 5F6	1.5 × 105	6.1 × 10−4	4.0 × 10−9	NB	NB	NB
mAb 18E11	2.0 × 105	1.9 × 10−2	9.3 × 10−8	1.5 × 105	3.4 × 102	2.2 × 10−7
Abr1	NB	NB	NB	1.8 × 105	4.79 × 105	2.64 × 10−10
Abr2	2.2 × 106	3.2 × 10−5	1.5 × 10−11	NB	NB	NB
Abr4	4.2 × 105	2.7 × 10−4	6.5 × 10−10	NB	NB	NB
N5	1.6 × 105	3.1 × 10−5	1.9 × 10−10	NB	NB	NB
N12	3.7 × 106	4.5 × 10−6	1.2 × 10−12	NB	NB	NB
Abr6	8.3 × 104	1.1 × 10−4	1.3 × 10−9	NB	NB	NB
3E	3.3 × 105	2.4 × 10−4	7.4 × 10−10	NB	NB	NB
10C	8.6 × 105	9.7 × 10−4	1.1 × 10−9	NB	NB	NB

NB = no binding observed; ^a Kd values are calculated from kd/ka; Binding constants for mAbs were determined using a bivalent model while those for sdAb were done with a Langmuir model.