Table II. Proteases identified from iRBC and postrupture vesicle membrane samples. A list of proteases identified with four or more unique peptides from (A) infected and (B) postrupture vesicle membrane proteomes are listed.
| 2A. Proteases identified in the proteomic analyses from iRBC membranes (I) | ||||
|---|---|---|---|---|
| Protease | Accession | Family | Organism | Peptides |
| Serine Repeat Antigen-5* | PFB0340c | Cysteine (C1) | P. falciparum | 182 |
| Calpain-1, Large subunit | gi 12408656 | Cysteine (C2) | H. sapiens | 22 |
| Serine Repeat Antigen-6* | PFB0335c | Cysteine (C1) | P. falciparum | 12 |
| 2B. Proteases identified from postrupture RBC membranes (R) | ||||
|---|---|---|---|---|
| Protease | Accession | Family | Organism | Peptides |
| Calpain-1, Large subunit | gi 12408656 | Cysteine (C2) | H. sapiens | 12 |
| Serine Repeat Antigen-6a | PFB0335c | Cysteine (C1) | P. falciparum | 5 |
| Serine Repeat Antigen-5a | PFB0340c | Cysteine (C1) | P. falciparum | 4 |
a Proteoytic activity has not been demonstrated for these proteins.