Fig. 2.

Identification of differential kinase protein expression across 34 HNSCC cell lines. a, examples for protein expression levels across all cell lines utilizing retention time aligned precursor ion intensities. Horizontal lines mark the median expression values. b, results of moderated F-statistics reveal kinases that are differentially expressed between cell lines (only proteins with F p values of <0.05 are listed). c, unsupervised clustering does not reveal any obvious grouping of differentially expressed kinases or cell lines, indicating strong differences between individual tumor biologies.