Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Oct 10;10(12):M111.012526. doi: 10.1074/mcp.M111.012526

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

Fig. 1. — Proteomics strategy to identify novel proteins at the fetal and maternal blood-tissue interfaces in the mouse placenta. A, Scheme of our applied workflow. Cationic silica-beads were perfused via the maternal aorta to reach trophoblast lined maternal blood spaces or via the umbilical cord to reach fetal endothelial-lined vessels in the placental labyrinth. Silica-beads were isolated from labyrinth tissue to obtain in vivo surface-associated proteins. Proteins isolated from beads were analyzed by MudPIT-based proteomics. B, A zoomed-in scatter plot representation of the entire dataset highlighting known markers of endothelial cells (EC; blue text) and trophoblast cells (TC; red text). Green data points were significantly associated with either the EC or TC surfaces (FDR p value ≤0.1), whereas gray data points did not significantly differ (FDR p value >0.1).