Colon inflammation (A), injury (B) scores, and representative images for WT (C) and Fat-1 mice (D) exposed to 3 cycles of DSS. Values are medians and the Wilcoxon rank sums for WT and Fat-1, respectively, were: 169 and 84 (A) and 213 and 88 (B), n = 12 (WT) or 15 (Fat-1). *Different from WT, P < 0.05 (Kruskal-Wallis test). Representative images are at 100× magnification. WT, wild type.