Table 1.
P0 maternal indices (mean ± SE; n = 7–11).
| Maternal index | Control | Control + 5 ppb PFOA | 1 mg/kg | 1 mg/kg + 5 ppb PFOA | 5 mg/kg | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Gestational weight gain (g) | 24.8 ± 1.2 | 25.0 ± 1.2 | 26.0 ± 1.2 | 27.0 ± 1.2 | 27.7 ± 1.2 | |||||
| Implants (no. per live litter) | 12.8 ± 0.5 | 12.7 ± 0.4 | 13.5 ± 0.7 | 14.0 ± 0.4 | 13.7 ± 0.6 | |||||
| Live fetuses (no. per live litter) | 12.0 ± 0.5 | 11.7 ± 0.4 | 12.9 ± 0.7 | 13.3 ± 0.5 | 10.0 ± 0.8* | |||||
| Prenatal loss (% per live litter) | 6.1 ± 1.8 | 7.8 ± 1.7 | 4.5 ± 1.7 | 5.1 ± 1.6 | 25.8 ± 5.6* | |||||
| Postnatal survival (% per live litter) | 96.1 ± 1.3 | 100 ± 0.0* | 98.8 ± 0.8 | 89.5 ± 6.4 | 72.7 ± 5.8* | |||||
| Mammary gland score (1–4 scale), PND22 | 2.4 ± 0.2 | 3.4 ± 0.1* | 3.0 ± 0.2* | 3.2 ± 0.2* | 3.9 ± 0.1* | |||||
| *p < 0.05 compared with control. | ||||||||||