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. 2011 Dec 14;6(12):e28344. doi: 10.1371/journal.pone.0028344

Figure 5. SL-E model results for an external pulse-chase bolus similar to the one in Fig. 3F .

Figure 5

Pools: Steryl-esters (X 33+X 34+X 35+X 40), Sterol (X 30+X 31+X 32+X 36+X 37+X 39). Ergosterol sub-populations: ergosterol in endoplasmic reticulum (X 32), ergosterol steryl-ester 1 (X 35), ergosterol associated with the complex sphingolipids (X 37), plasma membrane ergosterol in inner leaflet (X 39), ergosterol steryl-ester 2 (X 40). (A) Decrease to 1% in IPC synthase activity (X 133). Dynamic simulation for the steryl-esters pool and total sterols after pulse-chase bolus with labeled acetate. (B) Decrease to 1% in IPC synthase activity (X 133). (C) Decrease to a 1% in serine palmitoyl transferase activity (X 157). Dynamics simulation for the steryl- esters pool and total sterols after pulse-chase bolus with labeled acetate. (D) Decrease to a 1% in serine palmitoyl transferase activity (X 157).