Table 1. Allele and genotype distribution of CRHR1 and BDNF polymorphisms of recurrent MDD patients and controls.
Gene | SNP IDa | Position | Genotype | P | Allele | P | Odds Ratio | |||
(95%CI) | ||||||||||
AA | AG | GG | A | G | ||||||
BDND | rs6265 | chr11:27679916 MDD | 39 | 87 | 55 | 0.4301 | 165 | 197 | 0.4078 | 1.134 |
CON | 37 | 84 | 65 | 158 | 214 | (0.847–1.519) | ||||
CRHR1 | rs1876828 | chr17:43911525 MDD | 149 | 30 | 2 | 0.3126 | 328 | 34 | 0.1952 | 1.395 |
CON | 143 | 39 | 4 | 325 | 47 | (0.874–2.226) | ||||
rs242939 | chr17:43895579 MDD | 139 | 40 | 2 | 0.022 b | 318 | 44 | 0.018 b | 0.454 | |
CON | 166 | 18 | 2 | 350 | 22 | (0.266–0.775) |
SNP, single nucleotide polymorphism.
Bold numerals p-values after Bonferroni correction.