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. 2011 Dec 14;6(12):e28756. doi: 10.1371/journal.pone.0028756

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Ogiwara, Kohno.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Size fractionation of DNA fragments containing breakpoint junctions. The sizes of Type I–III products are shown on top. (B, C) Nucleotide sequences of the breakpoint junctions from NHEJ-impaired cells. (B) The sequences of the breakpoint junctions with the clone number and product type. The structure of the DNA ends generated by I-SceI is shown in the rectangle. (C) Type I, II and III products according to NHEJ protein impairment (shown as ratios after removing “Del>6bp” and “Other” products).