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. 2011 Dec 14;6(12):e29138. doi: 10.1371/journal.pone.0029138

Table 2. The 69 diatom MTs that are putatively derived from red algae, and red and/or green algae, clustered based on similar functions.

Cluster ID Size Putative function MT family Outgroup Algal origin HECTAR output
A02NE02 2 Protein translocase subunit secA IISP Prokaryote R -
A02NE04 1 Sodium bicarbonate cotransporter 3 AE Prokaryote R CHL
A02NE06 9 High-affinity nitrate transporter MFS Prokaryote R SA
A02NE19 2 Magnesium and cobalt efflux protein HCC Prokaryote R SP
A03NE28 2 Signal sequence-binding protein IISP Prokaryote R -
A04NE01 1 S-adenosylmethionine mitochondrial carrier protein MC Metazoa R -
A04NE02 1 Solute carrier family 25 member 36 MC Metazoa R -
A04NE03 1 HCO3 - transporter family AE Metazoa R SA
A02NE09 3 Uncharacterized sodium-dependent transporter BASS Prokaryote R+G SP
A03NE27 3 K+ efflux antiporter chloroplastic CPA2 Prokaryote R+G CHL
A02NE01 1 Adenosine 3-phospho 5-phosphosulfate transporter 1 DMT Metazoa R/G -
A02NE05 3 Chloride channel protein CLC-f ClC Prokaryote R/G MIT
A02NE07 4 Inner membrane protein chloroplastic Oxa1 Prokaryote R/G CHL
A02NE10 1 Protein grpE MPT Prokaryote R/G -
A02NE11 2 S-adenosylmethionine mitochondrial carrier protein MC Fungi R/G SP
A02NE12 1 Glutathione S-transferase DHAR2 CLIC Prokaryote R/G SA
A02NE13 2 Low affinity tryptophan permease HAAAP Prokaryote R/G SA
A02NE14 1 Sodium-dependent phosphate transport protein chloroplastic MFS Prokaryote R/G SP
A02NE15 5 Folate/biopterin transporter FBT Prokaryote R/G SA
A02NE16 2 YggT/hypothetical protein YggT Prokaryote R/G SP
A02NE17 4 ABC transporter D family member chloroplastic ABC Prokaryote R/G MIT
A02NE18 2 ABC transporter G family member 7 ABC Metazoa R/G SP
A02NE22 1 ATP synthase gamma chloroplastic F-ATPase Prokaryote R/G CHL
A03NE14 1 Anion exchanger AE Metazoa R/G -
A03NE23 3 Sodium bile acid cotransporter BASS Prokaryote R/G SP
A03NE26 3 Permease of the drug/metabolite transporter DMT Prokaryote R/G CHL
A03NE36 5 ABC transporter ATP-binding protein ABC Prokaryote R/G -
A03NE48 3 K+ efflux antiporter chloroplastic CPA2 Prokaryote R/G SP

Shown for each cluster is the identifier (Cluster ID), number of proteins within the cluster (Size), the putative function, the classification of MT family based on TransportDB, the outgroup used in phylogeny sorting, the putative algal origin of the proteins, i.e., Red (R), Red or Green (R/G), and Red and Green (R+G), and the protein target prediction using HECTAR, in which “CHL” denotes proteins targeting to chloroplast/plastid, “MIT” denotes proteins targeting to mitochondrion, “SP” denotes presence of signal peptide, “SA” denotes presence of Type II signal anchor, “-” denotes no N-terminal target peptide found. None of these proteins show evidence of mitochondrion-targeting. The abbreviation of MT family follows Table S1, according to http://www.membranetransport.org/.