FIG. 8.

Liver pathology. (A) Trichrome and (B) H&E staining were performed on liver samples 13 months post injection of 1.7×10¹² gc/kg scAAV8-dnMSTAT with liver-specific promoter (n=4) and compared with age-matched, untreated GRMD canines (n=3). Representative images are shown. To reduce redundancy, images from a subset of canines are presented for H&E staining. Low, 2.5×objective; medium, 10×objective; high, 40×objective. Scale bars: 400 μm for low, 200 μm for medium and high. Arrow indicates representative blood vessel (not all blood vessels are labeled). Color images available online at www.liebertonline.com/hum